The following ATP Citrate Lyase ELISA kits are useful research tools for the measurement of ATP citrate lyase in biological samples. In humans this protein is encoded by the ACLY gene. This protein is known to catalyze the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis. The canonical protein structure is reported to have an amino acid length of 1101 residues, a mass of 120.8 kDa, and is a member of the Succinate/malate CoA ligase beta subunit protein family; Succinate/malate CoA ligase alpha subunit protein family. Its subcellular location is known to be in the cytoplasm. As many as 3 protein isoforms have been reported. In certain instances, it is also post-translationally ubiquitinated, acetylated and phosphorylated. This protein may also be known as ATPCL, CLATP, ATP-citrate synthase, ATP-citrate (pro-S-)-lyase, citrate cleavage enzyme, and ACL.
The detection range for different ATP Citrate Lyase ELISA kits can vary, with some assays measuring target concentrations as low as 20 ng/L and as high as 40 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.