The following Thymidylate Synthetase ELISA kits are useful research tools for the measurement of thymidylate synthetase in biological samples. In humans this protein is encoded by the TYMS gene. This protein is known to catalyze the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway. The canonical protein structure is reported to have an amino acid length of 313 residues, a mass of 35.7 kDa, and is a member of the Thymidylate synthase protein family. Its subcellular location is known to be in the nucleus, mitochondria, and cytoplasm. As many as 3 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, Dyskeratosis congenita. This protein may also be known as HST422, TMS, TS, thymidylate synthase, TSase, and DKCD.
There are Thymidylate Synthetase ELISA kits that can detect a target at concentrations as low as 20 ng/L and as high as 100 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.