EFEMP1 ELISA kits are immunoassay tools for the measurement of the protein EGF containing fibulin extracellular matrix protein 1, which is encoded by the EFEMP1 gene in humans. Functionally, this protein is known to bind EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. The canonical protein structure is reported to have an amino acid length of 493 residues, a mass of 54.6 kDa, and is a member of the Fibulin protein family. It is known to be localized in the extracellular matrix and is secreted. As many as 5 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated. The EFEMP1 gene has been associated with the disease, Doyne honeycomb retinal dystrophy. Other alias names for this target include DRAD, FBLN3, FBNL, FIBL-3, MLVT, MTLV, S1-5, and DHRD.
The detection range for different EFEMP1 ELISA kits can vary, with some assays measuring target concentrations as low as 15.6 pg/mL and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.