The following phospholipase C beta 1 ELISA kits are useful research tools for the measurement of phospholipase C beta 1 in biological samples. In humans this protein is encoded by the PLCB1 gene. This protein is known to catalyze the hydrolysis of 1-phosphatidylinositol 4,5-bisphosphate into diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) and mediates intracellular signaling downstream of G protein-coupled receptors. The canonical protein structure is reported to have an amino acid sequence of 1216 residues and a mass of 138.6 kDa. Its subcellular location is known to be in the nucleus and cytoplasm. As many as 2 protein isoforms have been reported. In certain instances, it is also post-translationally palmitoylated. The gene encoding this protein has been associated with the disease, Developmental and epileptic encephalopathy. This protein may also be known as EIEE12, PI-PLC, PLC-154, PLC-I, PLC-beta-1, PLC154, PLCB1A, and DEE12.
Some phospholipase C beta 1 ELISA kits can detect targets at levels as low as 20 ng/L and as high as 20 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.