UMOD ELISA kits are immunoassay tools for the measurement of the protein uromodulin, which is encoded by the UMOD gene in humans. Functionally, this protein is known to be involved in the apoptotic pathway and autophagy pathways. The canonical protein structure is reported to have an amino acid sequence of 640 residues and a mass of 69.8 kDa. It is known to be localized in the cell membrane and is reported to be expressed in the tubular cells of the kidney. As many as 5 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated and cleaved. The UMOD gene has been associated with the disease, Tubulointerstitial kidney disease. Other alias names for this target include ADTKD1, FJHN, HNFJ, HNFJ1, MCKD2, THGP, THP, and ADMCKD2.
There are UMOD ELISA kits that can detect a target at concentrations as low as 2 ng/L and as high as 900 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.