The following DNA methyltransferase 1 ELISA kits are useful research tools for the measurement of DNA methyltransferase 1 in biological samples. In humans this protein is encoded by the DNMT1 gene. This protein has been described to function in the regulation of gene expression and the regulation of transcription. The canonical protein structure is reported to have an amino acid length of 1616 residues, a mass of 183.2 kDa, and is a member of the C5-methyltransferase protein family. Its subcellular location is known to be in the nucleus. In addition, it is widely expressed across many tissue types. As many as 3 protein isoforms have been reported. In certain instances, it is also post-translationally ubiquitinated, sumoylated, acetylated and phosphorylated. The gene encoding this protein has been associated with the disease, Neuropathy. This protein may also be known as ADCADN and AIM.
The detection range for different DNA methyltransferase 1 ELISA kits can vary, with some assays measuring target concentrations as low as 0.15 ng/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.