The following Paired Box 8 ELISA kits are useful research tools for the measurement of paired box 8 in biological samples. In humans this protein is encoded by the PAX8 gene. This protein is reported to be a transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cells. The canonical protein structure is reported to have an amino acid sequence of 450 residues and a mass of 48.2 kDa. Its subcellular location is known to be in the nucleus. In addition, it is reported to be expressed in the excretory system, thyroid gland and Wilms tumors. As many as 5 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, Hypothyroidism. This protein may also be known as paired box protein Pax-8 and paired domain gene 8.
Some Paired Box 8 ELISA kits can detect targets at levels as low as 15.6 pg/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.