The following Janus kinase 1 ELISA kits are useful research tools for the measurement of Janus kinase 1 in biological samples. In humans this protein is encoded by the JAK1 gene. This protein has been described to function in cell differentiation and viral immune response. The canonical protein structure is reported to have an amino acid length of 1154 residues, a mass of 133.3 kDa, and is a member of the Tyr protein kinase protein family. Its subcellular location is known to be in the membrane. In addition, it is noted to be expressed at higher levels in primary colon tumors than in normal colon tissue. In certain instances, it is also post-translationally ubiquitinated and phosphorylated. The gene encoding this protein has been associated with the disease, Autoinflammation, immune dysregulation, and eosinophilia. This protein may also be known as JAK1A, JAK1B, JTK3, tyrosine-protein kinase JAK1, and AIIDE.
The detection range for different Janus kinase 1 ELISA kits can vary, with some assays measuring target concentrations as low as 0.15 ng/mL and as high as 50 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.