Undercarboxylated osteocalcin ELISA kits are assays designed to detect the undercarboxylated form of the protein hormone osteocalcin. Osteocalcin is a vitamin K dependent hormone found in dentin and bone. It is secreted by osteoblasts and, when carboxylated, can bind directly to calcium and become concentrated in bones. It has been linked to bone mineralization and is used as a biomarker of bone formation and vitamin K levels. Undercarboxylated osteocalcin is released into the bloodstream and has been shown to regulate insulin sensitivity and secretion. Visit the supplier page for more information about detection range and reactivity