HPGDS ELISA kits are immunoassay tools for the measurement of the protein hematopoietic prostaglandin D synthase, which is encoded by the HPGDS gene in humans. Functionally, this protein is reported to be a bifunctional enzyme, which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. The canonical protein structure is reported to have an amino acid length of 199 residues, a mass of 23.3 kDa, and is a member of the Sigma protein family. It is known to be localized in the cytoplasm and is reported to be expressed in a number of megakaryocytic cell lines but not in platelets. Other alias names for this target include GSTS1, GSTS1-1, PGD2, PGDS, GST class-sigma, and GSTS.
The detection range for different HPGDS ELISA kits can vary, with some assays measuring target concentrations as low as 15.63 pg/mL and as high as 75 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.