The following uromodulin ELISA kits are useful research tools for the measurement of uromodulin in biological samples. In humans this protein is encoded by the UMOD gene. This protein has been described to function in the apoptotic pathway and autophagy pathways. The canonical protein structure is reported to have an amino acid sequence of 640 residues and a mass of 69.8 kDa. Its subcellular location is known to be in the cell membrane. In addition, it is reported to be expressed in the tubular cells of the kidney. As many as 5 protein isoforms have been reported. In certain instances, it is also post-translationally N-glycosylated and cleaved. The gene encoding this protein has been associated with the disease, Tubulointerstitial kidney disease. This protein may also be known as ADTKD1, FJHN, HNFJ, HNFJ1, MCKD2, THGP, THP, and ADMCKD2.
There are uromodulin ELISA kits that can detect a target at concentrations as low as 2 ng/L and as high as 900 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.