These topoisomerase (DNA) I ELISA kits are immunodetection tools for measuring specific protein levels in biological samples. topoisomerase (DNA) I is an alias of the human TOP1 gene, which encodes the protein, DNA topoisomerase I. Notably, topoisomerase (DNA) I is known to play a role in chromatin remodeling and DNA replication, among other functions. The TOP1 protein is described to be 765 amino acid residues in length and 90.7 kilodaltons in mass. It is localized to the nucleus of the cell. This protein is known to be sumoylated and phosphorylated. Other names for this target antigen include TOPI, DNA topoisomerase 1, and Scl-70 antigen.
There are topoisomerase (DNA) I ELISA kits that can detect a target at concentrations as low as 20 ng/L and as high as 10 ng/mL. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.