The following Ubiquilin 4 ELISA kits are useful research tools for the measurement of ubiquilin 4 in biological samples. In humans this protein is encoded by the UBQLN4 gene. This protein is a reported regulator of protein degradation that mediates the proteasomal targeting of misfolded, mislocalized or accumulated proteins. The canonical protein structure is reported to have an amino acid sequence of 601 residues and a mass of 63.9 kDa. Its subcellular location is known to be in the nucleus, cytoplasmic vesicles, ER, and cytoplasm. In addition, it is reported to be highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver. As many as 2 protein isoforms have been reported. In certain instances, it is also post-translationally ubiquitinated and phosphorylated. The gene encoding this protein has been associated with the disease, Amyotrophic lateral sclerosis. This protein may also be known as ataxin-1 ubiquitin-like interacting protein, ataxin-1 ubiquitin-like-interacting protein A1U, connexin43-interacting protein of 75 kDa, and ataxin-1 interacting ubiquitin-like protein.
The detection range for different Ubiquilin 4 ELISA kits can vary, with some assays measuring target concentrations as low as 0.1 ng/mL and as high as 40 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.