The following Fukutin Related Protein ELISA kits are useful research tools for the measurement of fukutin related protein in biological samples. In humans this protein is encoded by the FKRP gene. This protein is known to catalyze the transfer of a ribitol 5-phosphate from CDP-L-ribitol to the ribitol 5-phosphate previously attached by FKTN/fukutin to the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). The canonical protein structure is reported to have an amino acid length of 495 residues, a mass of 54.6 kDa, and is a member of the LicD transferase protein family. Its subcellular location is known to be in the cell membrane, ER, golgi, cytoplasm, and is secreted. In addition, it is reported to be expressed in the retina. In certain instances, it is also post-translationally N-glycosylated. The gene encoding this protein has been associated with the disease, Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies. This protein may also be known as ribitol 5-phosphate transferase FKRP and ribitol-5-phosphate transferase.
The detection range for different Fukutin Related Protein ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.