The following triggering receptor expressed on myeloid cells 2 ELISA kits are useful research tools for the measurement of triggering receptor expressed on myeloid cells 2 in biological samples. In humans this protein is encoded by the TREM2 gene. This protein has been described to function in the apoptotic pathway and carbohydrate metabolism and homeostasis. The canonical protein structure is reported to have an amino acid sequence of 230 residues and a mass of 25.4 kDa. Its subcellular location is known to be in the cell membrane and is secreted. In addition, it is reported to be expressed in the brain, specifically in microglia and in the fusiform gyrus. As many as 3 protein isoforms have been reported. In certain instances, it is also post-translationally cleaved and glycosylated. The gene encoding this protein has been associated with the disease, Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy. This protein may also be known as Trem2a, Trem2b, Trem2c, triggering receptor expressed on monocytes 2, triggering receptor expressed on myeloid cells 2a, and PLOSL2.
There are triggering receptor expressed on myeloid cells 2 ELISA kits that can detect a target at concentrations as low as 10.97 pg/mL and as high as 50 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.