EIF4E ELISA kits are immunoassay tools for the measurement of the protein eukaryotic translation initiation factor 4E, which is encoded by the EIF4E gene in humans. Functionally, this protein is known to recognize and bind the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. The canonical protein structure is reported to have an amino acid length of 217 residues, a mass of 25.1 kDa, and is a member of the Eukaryotic initiation factor 4E protein family. It is known to be localized in the nucleus and cytoplasm. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. The EIF4E gene has been associated with the disease, Autism. Other alias names for this target include CBP, EIF4EL1, EIF4F, eIF-4F 25 kDa subunit, and AUTS19.
The detection range for different EIF4E ELISA kits can vary, with some assays measuring target concentrations as low as 7 ng/L and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.