PTCHD1 ELISA kits are immunoassay tools for the measurement of the protein patched domain containing 1, which is encoded by the PTCHD1 gene in humans. Functionally, this protein is known to be required for the development and function of the thalamic reticular nucleus (TRN), a part of the thalamus that is critical for thalamocortical transmission, generation of sleep rhythms, sensorimotor processing and attention. The canonical protein structure is reported to have an amino acid length of 888 residues, a mass of 101.3 kDa, and is a member of the Patched protein family. It is known to be localized in the cell membrane and is reported to be widely expressed including in various regions of the brain with highest expression in the gray and white cerebellum, followed by the cerebellar vermis and the pituitary gland. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated. The PTCHD1 gene has been associated with the disease, Autism. Other alias names for this target include patched domain-containing protein 1.
Some PTCHD1 ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.