The following pantothenate kinase 2 ELISA kits are useful research tools for the measurement of pantothenate kinase 2 in biological samples. In humans this protein is encoded by the PANK2 gene. This protein is reported to be a mitochondrial isoform that catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis. The canonical protein structure is reported to have an amino acid length of 570 residues, a mass of 62.7 kDa, and is a member of the Type II pantothenate kinase protein family. Its subcellular location is known to be in the nucleus and mitochondria. In addition, it is notably expressed in the brain. In certain instances, it is also post-translationally cleaved. The gene encoding this protein has been associated with the disease, Neurodegeneration with brain iron accumulation. This protein may also be known as Hallervorden-Spatz syndrome, pantothenate kinase-associated neurodegeneration, pantothenic acid kinase 2, and pantothenate kinase 2, mitochondrial.
The detection range for different pantothenate kinase 2 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.