The following SMAD Family Member 3 ELISA kits are useful research tools for the measurement of SMAD family member 3 in biological samples. In humans this protein is encoded by the SMAD3 gene. This protein is a known receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. The canonical protein structure is reported to have an amino acid length of 425 residues, a mass of 48.1 kDa, and is a member of the Dwarfin/SMAD protein family. Its subcellular location is known to be in the nucleus and cytoplasm. As many as 4 protein isoforms have been reported. In certain instances, it is also post-translationally ubiquitinated, acetylated and phosphorylated. The gene encoding this protein has been associated with the disease, Colorectal cancer. This protein may also be known as HsT17436, JV15-2, LDS1C, LDS3, MADH3, hMAD-3, hSMAD3, and HSPC193.
The detection range for different SMAD Family Member 3 ELISA kits can vary, with some assays measuring target concentrations as low as 21.01 ng/L and as high as 500 µg/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.