MAG ELISA kits are immunoassay tools for the measurement of the protein myelin associated glycoprotein, which is encoded by the MAG gene in humans. Functionally, this protein is reported to be an adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (By similarity). The canonical protein structure is reported to have an amino acid length of 626 residues, a mass of 69.1 kDa, and is a member of the SIGLEC (sialic acid binding Ig-like lectin) protein family. It is known to be localized in the cell membrane. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated, ubiquitinated and phosphorylated. The MAG gene has been associated with the disease, Spastic paraplegia. Other alias names for this target include S-MAG, SIGLEC-4A, SIGLEC4A, SPG75, sialic acid binding Ig-like lectin 4A, and GMA.
Some MAG ELISA kits can detect targets at levels as low as 10 pg/mL and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.