SKP2 ELISA kits are immunoassay tools for the measurement of the protein S-phase kinase associated protein 2, which is encoded by the SKP2 gene in humans. Functionally, this protein is reported to be a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. The canonical protein structure is reported to have an amino acid sequence of 424 residues and a mass of 47.8 kDa. It is known to be localized in the nucleus and cytoplasm. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated, acetylated and cleaved. Other alias names for this target include FBXL1, FLB1, p45, CDK2/cyclin A-associated protein p45, F-box/LRR-repeat protein 1, and FBL1.
Some SKP2 ELISA kits can detect targets at levels as low as 0.15 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.