The following Ribonuclease T2 ELISA kits are useful research tools for the measurement of ribonuclease T2 in biological samples. In humans this protein is encoded by the RNASET2 gene. This protein is a reported ribonuclease that plays an essential role in innate immune response by recognizing and degrading RNAs from microbial pathogens that are subsequently sensed by TLR8. The canonical protein structure is reported to have an amino acid length of 256 residues, a mass of 29.5 kDa, and is a member of the RNase T2 protein family. Its subcellular location is known to be in the mitochondria, ER, lysosomes, and is secreted. In addition, it is ubiquitously expressed across many tissue types. As many as 2 protein isoforms have been reported. In certain instances, it is also post-translationally glycosylated. The gene encoding this protein has been associated with the disease, Leukoencephalopathy. This protein may also be known as bA514O12.3, ribonuclease 6, and RNASE6PL.
There are ribonuclease T2 ELISA kits that can detect a target at concentrations as low as 13.7 pg/mL and as high as 50 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.