The following Kynureninase ELISA kits are useful research tools for the measurement of kynureninase in biological samples. In humans this protein is encoded by the KYNU gene. This protein is known to catalyze the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. The canonical protein structure is reported to have an amino acid length of 465 residues, a mass of 52.4 kDa, and is a member of the Kynureninase protein family. Its subcellular location is known to be in the cytoplasm. In addition, it is reported to be expressed in all tissues tested (heart, brain placenta, lung, liver, skeletal muscle, kidney and pancreas). As many as 2 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, Hydroxykynureninuria. This protein may also be known as KYNUU and VCRL2.
There are kynureninase ELISA kits that can detect a target at concentrations as low as 4.4 pg/mL and as high as 150 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.