The following nitrilase 1 ELISA kits are useful research tools for the measurement of nitrilase 1 in biological samples. In humans this protein is encoded by the NIT1 gene. This protein is known to catalyze the hydrolysis of the amide bond in N-(4-oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione. The canonical protein structure is reported to have an amino acid length of 327 residues, a mass of 35.9 kDa, and is a member of the NIT1/NIT2 protein family. Its subcellular location is known to be in the mitochondria and cytoplasm. In addition, it is notably expressed in fetal brain, placenta, liver, skeletal muscle, kidney and pancreas. As many as 5 protein isoforms have been reported. This protein may also be known as deaminated glutathione amidase and dGSH amidase.
Some nitrilase 1 ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.