The following Histone Deacetylase 6 ELISA kits are useful research tools for the measurement of histone deacetylase 6 in biological samples. In humans this protein is encoded by the HDAC6 gene. This protein is known to be important for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). The canonical protein structure is reported to have an amino acid length of 1215 residues, a mass of 131.4 kDa, and is a member of the Histone deacetylase protein family. Its subcellular location is known to be in the nucleus and cytoplasm. As many as 2 protein isoforms have been reported. In certain instances, it is also post-translationally ubiquitinated, sumoylated, acetylated and phosphorylated. The gene encoding this protein has been associated with the disease, Chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia. This protein may also be known as HD6, JM21, PPP1R90, protein phosphatase 1, regulatory subunit 90, tubulin-lysine deacetylase HDAC6, and CPBHM.
The detection range for different histone deacetylase 6 ELISA kits can vary, with some assays measuring target concentrations as low as 15 ng/L and as high as 40 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.