The following dihydrofolate reductase ELISA kits are useful research tools for the measurement of dihydrofolate reductase in biological samples. In humans this protein is encoded by the DHFR gene. This protein is known to be a key enzyme in folate metabolism. The canonical protein structure is reported to have an amino acid length of 187 residues, a mass of 21.5 kDa, and is a member of the Dihydrofolate reductase protein family. Its subcellular location is known to be in the mitochondria and cytoplasm. In addition, it is found to be widely expressed in fetal and adult tissues, including throughout the fetal and adult brains and whole blood. As many as 2 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, Megaloblastic anemia due to dihydrofolate reductase deficiency. This protein may also be known as DHFRP1, DYR, and DHFR1.
Some dihydrofolate reductase ELISA kits can detect targets at levels as low as 20 ng/L and as high as 70 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.