CASR ELISA kits are immunoassay tools for the measurement of the protein calcium sensing receptor, which is encoded by the CASR gene in humans. Functionally, this protein is reported to be a G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis. The canonical protein structure is reported to have an amino acid length of 1078 residues, a mass of 120.7 kDa, and is a member of the G-protein coupled receptor 3 protein family. It is known to be localized in the cell membrane and is reported to be expressed in the temporal lobe, frontal lobe, parietal lobe, hippocampus, and cerebellum. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated and ubiquitinated. The CASR gene has been associated with the disease, Hypocalciuric hypercalcemia. Other alias names for this target include EIG8, FHH, FIH, GPRC2A, HHC, HHC1, HYPOC1, and CAR.
Some CASR ELISA kits can detect targets at levels as low as 31.25 pg/mL and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.