The following Histone Deacetylase 8 ELISA kits are useful research tools for the measurement of histone deacetylase 8 in biological samples. In humans this protein is encoded by the HDAC8 gene. This protein is reported to be a histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). The canonical protein structure is reported to have an amino acid length of 377 residues, a mass of 41.8 kDa, and is a member of the Histone deacetylase protein family. Its subcellular location is known to be in the nucleus and cytoplasm. In addition, it is reported to be weakly expressed in most tissues. As many as 6 protein isoforms have been reported. In certain instances, it is also post-translationally phosphorylated. The gene encoding this protein has been associated with the disease, Cornelia de Lange syndrome. This protein may also be known as protein deacetylase HDAC8, protein decrotonylase HDAC8, and histone deacetylase-like 1.
Some histone deacetylase 8 ELISA kits can detect targets at levels as low as 0.06 ng/mL and as high as 50 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.