The beta-site APP-cleaving enzyme 2 ELISA kits listed below utilize specific antibodies for the plate-based assay of beta-site APP-cleaving enzyme 2 in various samples. beta-site APP-cleaving enzyme 2 is another term for the BACE2 gene, which encodes the protein, beta-secretase 2 in humans. It has been reported that beta-site APP-cleaving enzyme 2 plays a role in carbohydrate metabolism and homeostasis and proteolysis, among other functions. Structurally, the BACE2 protein is 518 amino acid residues in length and 56.2 kilodaltons in mass. However, as many as 5 protein isoforms have been identified. It is localized to the ER, golgi, and cell membrane of the cell. In terms of tissue specificity, it is notably expressed in the brain. This protein is known to be glycosylated and cleaved. Other names for this target antigen include AEPLC, ALP56, and ASP1.
Some beta-site APP-cleaving enzyme 2 ELISA kits can detect targets at levels as low as 0.312 ng/mL and as high as 20 ng/mL. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.