The following NK3 Homeobox 2 ELISA kits are useful research tools for the measurement of NK3 homeobox 2 in biological samples. In humans this protein is encoded by the NKX3-2 gene. This protein is reported to be a transcriptional repressor that acts as a negative regulator of chondrocyte maturation. The canonical protein structure is reported to have an amino acid length of 333 residues, a mass of 34.8 kDa, and is a member of the NK-3 homeobox protein family. Its subcellular location is known to be in the nucleus. In addition, it is reported be expressed at highest levels in cartilage, bone (osteosarcoma) and gut (small intestine and colon), whereas moderate expression is seen in trachea and brain. The gene encoding this protein has been associated with the disease, Spondylo-megaepiphyseal-metaphyseal dysplasia. This protein may also be known as NKX3.2, NKX3B, SMMD, homeobox protein Nkx-3.2, bagpipe homeobox protein homolog 1, and BAPX1.
The detection range for different NK3 Homeobox 2 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.