ATG4B ELISA kits are immunoassay tools for the measurement of the protein autophagy related 4B cysteine peptidase, which is encoded by the ATG4B gene in humans. Functionally, this protein is reported to be a cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins. The canonical protein structure is reported to have an amino acid length of 393 residues, a mass of 44.3 kDa, and is a member of the Peptidase C54 protein family. It is known to be localized in the cytoplasmic vesicles, mitochondria, ER, and cytoplasm. As many as 5 protein isoforms have been reported. The protein has been noted to be post-translationally O-glycosylated, ubiquitinated and phosphorylated. Other alias names for this target include AUTL1, HsAPG4B, cysteine protease ATG4B, APG4 autophagy 4 homolog B, ATG4 autophagy related 4 homolog B, and APG4B.
The detection range for different ATG4B ELISA kits can vary, with some assays measuring target concentrations as low as 0.05 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.