CDKL5 ELISA kits are immunoassay tools for the measurement of the protein cyclin dependent kinase like 5, which is encoded by the CDKL5 gene in humans. Functionally, this protein is known to mediate phosphorylation of MECP2. The canonical protein structure is reported to have an amino acid length of 960 residues, a mass of 107.5 kDa, and is a member of the CMGC Ser/Thr protein kinase protein family. It is known to be localized in the nucleus and cytoplasm and is reported to be expressed in the brain, lung, kidney, prostate, ovary, placenta, pancreas and testis; [Isoform 2]: Predominant transcript in the brain. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. The CDKL5 gene has been associated with the disease, Developmental and epileptic encephalopathy. Other alias names for this target include DEE2, EIEE2, ISSX, STK9, cyclin dependent kinase 5 transcript, and CFAP247.
The detection range for different CDKL5 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.