The following Interferon Regulatory Factor 8 ELISA kits are useful research tools for the measurement of interferon regulatory factor 8 in biological samples. In humans this protein is encoded by the IRF8 gene. This protein is reported to be a transcription factor that specifically binds to the upstream regulatory region of type I interferon (IFN) and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). The canonical protein structure is reported to have an amino acid length of 426 residues, a mass of 48.4 kDa, and is a member of the IRF protein family. Its subcellular location is known to be in the nucleus and cytoplasm. In addition, it is reported to be highly expressed in the lymphoid tissues. In certain instances, it is also post-translationally ubiquitinated and sumoylated. The gene encoding this protein has been associated with the disease, Immunodeficiency. This protein may also be known as ICSBP, ICSBP1, IMD32A, IMD32B, interferon consensus sequence binding protein 1, and H-ICSBP.
The detection range for different Interferon Regulatory Factor 8 ELISA kits can vary, with some assays measuring target concentrations as low as 5 ng/L and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.