ATG16L1 ELISA kits are immunoassay tools for the measurement of the protein autophagy related 16 like 1, which is encoded by the ATG16L1 gene in humans. Functionally, this protein is known to play an important role in both canonical and non-canonical autophagy: interacts with ATG12-ATG5 to mediate the lipidation to ATG8 family proteins (MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAPL1, GABARAPL2 and GABARAP). The canonical protein structure is reported to have an amino acid length of 607 residues, a mass of 68.3 kDa, and is a member of the WD repeat ATG16 protein family. It is known to be localized in the membrane, lysosomes and cytoplasm. As many as 5 protein isoforms have been reported. The protein has been noted to be post-translationally cleaved and phosphorylated. The ATG16L1 gene has been associated with the disease, Inflammatory bowel disease. Other alias names for this target include ATG16A, ATG16L, IBD10, WDR30, autophagy-related protein 16-1, and APG16L.
The detection range for different ATG16L1 ELISA kits can vary, with some assays measuring target concentrations as low as 0.15 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.