The following 24-dehydrocholesterol reductase ELISA kits are useful research tools for the measurement of 24-dehydrocholesterol reductase in biological samples. In humans this protein is encoded by the DHCR24 gene. This protein is known to catalyze the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The canonical protein structure is reported to have an amino acid length of 516 residues, a mass of 60.1 kDa, and is a member of the FAD-binding oxidoreductase/transferase type 4 protein family. Its subcellular location is known to be in the ER and golgi. In addition, it is reported to be highly expressed in the brain and adrenal gland with moderate expression in liver, lung, spleen, prostate and spinal cord. As many as 2 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, Desmosterolosis. This protein may also be known as Nbla03646, SELADIN1, seladin-1, delta(24)-sterol reductase, 3 beta-hydroxysterol delta 24-reductase, and DCE.
Some 24-dehydrocholesterol reductase ELISA kits can detect targets at levels as low as 78 pg/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.