The following dystrobrevin binding protein 1 ELISA kits are useful research tools for the measurement of dystrobrevin binding protein 1 in biological samples. In humans this protein is encoded by the DTNBP1 gene. This protein is a known component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. The canonical protein structure is reported to have an amino acid length of 351 residues, a mass of 39.5 kDa, and is a member of the Dysbindin protein family. Its subcellular location is known to be in the cell membrane, nucleus, cytoplasmic vesicles, ER, and cytoplasm. In addition, it is notably expressed in the brain, in neurons and in neuropil. In certain instances, it is also post-translationally ubiquitinated and phosphorylated. The gene encoding this protein has been associated with the disease, Hermansky-Pudlak syndrome. This protein may also be known as BLOC-1 subunit 8, Hermansky-Pudlak syndrome 7 protein, biogenesis of lysosomal organelles complex-1, subunit 8, biogenesis of lysosome-related organelles complex 1 subunit 8, dysbindin-1, and dysbindin.
The detection range for different dystrobrevin binding protein 1 ELISA kits can vary, with some assays measuring target concentrations as low as 15.6 pg/mL and as high as 5000 pg/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.