The following aprataxin ELISA kits are useful research tools for the measurement of aprataxin in biological samples. In humans this protein is encoded by the APTX gene. This protein is known to be a DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. The canonical protein structure is reported to have an amino acid sequence of 356 residues and a mass of 40.7 kDa. Its subcellular location is known to be in the nucleus. In addition, it is reported to be widely expressed, detected in liver, kidney and lymph node. As many as 13 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, Ataxia-oculomotor apraxia syndrome. This protein may also be known as AOA1, AXA1, EAOH, EOAHA, FHA-HIT, forkhead-associated domain histidine triad-like protein, and AOA.
Some aprataxin ELISA kits can detect targets at levels as low as 31.25 pg/mL and as high as 2000 pg/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.