TCOF1 ELISA kits are immunoassay tools for the measurement of the protein treacle ribosome biogenesis factor 1, which is encoded by the TCOF1 gene in humans. Functionally, this protein is reported to be a nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification. The canonical protein structure is reported to have an amino acid sequence of 1488 residues and a mass of 152.1 kDa. It is known to be localized in the nucleus. As many as 8 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated and phosphorylated. The TCOF1 gene has been associated with the disease, Treacher Collins syndrome. Other alias names for this target include TCS, TCS1, treacle, treacle protein, Treacher Collins syndrome protein, and MFD1.
The detection range for different TCOF1 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.