OPTN ELISA kits are immunoassay tools for the measurement of the protein optineurin, which is encoded by the OPTN gene in humans. Functionally, this protein is known to play an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. The canonical protein structure is reported to have an amino acid sequence of 577 residues and a mass of 65.9 kDa. It is known to be localized in the cytoplasmic vesicles, golgi, and cytoplasm. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. The OPTN gene has been associated with the disease, Glaucoma. Other alias names for this target include FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP, E3-14.7K-interacting protein, and ALS12.
The detection range for different OPTN ELISA kits can vary, with some assays measuring target concentrations as low as 20 ng/L and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.