NKX2-5 ELISA kits are immunoassay tools for the measurement of the protein NK2 homeobox 5, which is encoded by the NKX2-5 gene in humans. Functionally, this protein is known to be a transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity). The canonical protein structure is reported to have an amino acid length of 324 residues, a mass of 34.9 kDa, and is a member of the NK-2 homeobox protein family. It is known to be localized in the nucleus and is found to be preferentially expressed in the heart.. As many as 3 protein isoforms have been reported. The NKX2-5 gene has been associated with the disease, Atrial septal defect. Other alias names for this target include CSX, CSX1, HLHS2, NKX2.5, NKX2E, NKX4-1, VSD3, and CHNG5.
The detection range for different NKX2-5 ELISA kits can vary, with some assays measuring target concentrations as low as 15 ng/L and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.