EDN3 ELISA kits are immunoassay tools for the measurement of the protein endothelin 3, which is encoded by the EDN3 gene in humans. Functionally, this protein is known to be involved in axon guidance and cell proliferation. The canonical protein structure is reported to have an amino acid length of 238 residues, a mass of 25.5 kDa, and is a member of the Endothelin/sarafotoxin protein family. It is known to be secreted and is reported to be expressed in trophoblasts and placental stem villi vessels, but not in cultured placental smooth muscle cells. As many as 3 protein isoforms have been reported. The EDN3 gene has been associated with the disease, Hirschsprung disease. Other alias names for this target include ET3, HSCR4, PPET3, WS4B, preproendothelin-3, and ET-3.
Some EDN3 ELISA kits can detect targets at levels as low as 0.5 ng/L and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.