CSF1R ELISA kits are immunoassay tools for the measurement of the protein colony stimulating factor 1 receptor, which is encoded by the CSF1R gene in humans. Functionally, this protein is reported to be a tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. The canonical protein structure is reported to have an amino acid length of 972 residues, a mass of 108 kDa, and is a member of the Tyr protein kinase protein family. It is known to be localized in the cell membrane and is reported to be expressed in bone marrow and in differentiated blood mononuclear cells. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated, ubiquitinated and phosphorylated. Other alias names for this target include C-FMS, CD115, CSFR, FIM2, FMS, GPSC, HDLS, and BANDDOS.
The detection range for different CSF1R ELISA kits can vary, with some assays measuring target concentrations as low as 2.5 pg/mL and as high as 80 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.