SCN1A ELISA kits are immunoassay tools for the measurement of the protein sodium voltage-gated channel alpha subunit 1, which is encoded by the SCN1A gene in humans. Functionally, this protein is known to mediate the voltage-dependent sodium ion permeability of excitable membranes. The canonical protein structure is reported to have an amino acid length of 2009 residues, a mass of 229 kDa, and is a member of the Sodium channel (TC 1.A.1.10) protein family. It is known to be localized in the cell membrane. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated and glycosylated. The SCN1A gene has been associated with the disease, Generalized epilepsy with febrile seizures plus. Other alias names for this target include DEE6A, DEE6B, DRVT, EIEE6, FEB3A, FHM3, GEFSP2, and DEE6.
The detection range for different SCN1A ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.