HTT ELISA kits are immunoassay tools for the measurement of the protein huntingtin, which is encoded by the HTT gene in humans. Functionally, this protein is known to be involved in the apoptotic pathway and Golgi organization. The canonical protein structure is reported to have an amino acid length of 3142 residues, a mass of 347.6 kDa, and is a member of the Huntingtin protein family. It is known to be localized in the nucleus, cytoplasmic vesicles, and cytoplasm and is reported to be expressed in the brain cortex. The protein has been noted to be post-translationally ubiquitinated, cleaved, myristoylated and phosphorylated. The HTT gene has been associated with the disease, Huntington disease. Other alias names for this target include IT15, LOMARS, huntington disease protein, and HD.
The detection range for different HTT ELISA kits can vary, with some assays measuring target concentrations as low as 7 ng/L and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.