HMGCL ELISA kits are immunoassay tools for the measurement of the protein 3-hydroxy-3-methylglutaryl-CoA lyase, which is encoded by the HMGCL gene in humans. Functionally, this protein is known to be involved in the metabolism of lipids. The canonical protein structure is reported to have an amino acid length of 325 residues, a mass of 34.4 kDa, and is a member of the HMG-CoA lyase protein family. It is known to be localized in the mitochondria and is reported be highly expressed in liver. As many as 3 protein isoforms have been reported. The HMGCL gene has been associated with the disease, 3-hydroxy-3-methylglutaryl-CoA lyase deficiency. Other alias names for this target include hydroxymethylglutaryl-CoA lyase, mitochondrial, 3-hydroxy-3-methylglutarate-CoA lyase, 3-hydroxymethyl-3-methylglutaryl-CoA lyase, 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase, and HL.
The detection range for different HMGCL ELISA kits can vary, with some assays measuring target concentrations as low as 15 ng/L and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.