AAK1 ELISA kits are immunoassay tools for the measurement of the protein AP2 associated kinase 1, which is encoded by the AAK1 gene in humans. Functionally, this protein is reported to regulate clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. The canonical protein structure is reported to have an amino acid length of 961 residues, a mass of 103.9 kDa, and is a member of the Ser/Thr protein kinase protein family. It is known to be localized in the cell membrane and is notably expressed in the brain, heart and liver. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. Other alias names for this target include AP2-associated protein kinase 1 and adaptor-associated kinase 1.
Some AAK1 ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.