ESPL1 ELISA kits are immunoassay tools for the measurement of the protein extra spindle pole bodies like 1, separase, which is encoded by the ESPL1 gene in humans. Functionally, this protein is reported to be a caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. The canonical protein structure is reported to have an amino acid sequence of 2120 residues and a mass of 233.2 kDa. It is known to be localized in the nucleus and cytoplasm. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally cleaved and phosphorylated. Other alias names for this target include SEPA, separin, caspase-like protein ESPL1, extra spindle pole bodies 1, separase, extra spindle pole bodies homolog 1, and ESP1.
Some ESPL1 ELISA kits can detect targets at levels as low as 15.6 pg/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.