XRCC1 ELISA kits are immunoassay tools for the measurement of the protein X-ray repair cross complementing 1, which is encoded by the XRCC1 gene in humans. Functionally, this protein is known to be a scaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes. The canonical protein structure is reported to have an amino acid sequence of 633 residues and a mass of 69.5 kDa. It is known to be localized in the nucleus and is reported to be expressed in fibroblasts, retinal pigmented epithelial cells and lymphoblastoid cells. The protein has been noted to be post-translationally sumoylated and phosphorylated. The XRCC1 gene has been associated with the disease, Spinocerebellar ataxia. Other alias names for this target include SCAR26, DNA repair protein XRCC1, X-ray repair complementing defective repair in Chinese hamster cells 1, X-ray repair cross-complementing protein 1, and RCC.
The detection range for different XRCC1 ELISA kits can vary, with some assays measuring target concentrations as low as 15.6 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.