The tripeptidyl peptidase I ELISA kits listed below utilize specific antibodies for the plate-based assay of tripeptidyl peptidase I in various samples. tripeptidyl peptidase I is another term for the TPP1 gene, which encodes the protein, tripeptidyl peptidase 1 in humans. It has been reported that tripeptidyl peptidase I plays a role in nervous system development and epithelial cell differentiation, among other functions. Structurally, the TPP1 protein is 563 amino acid residues in length and 61.2 kilodaltons in mass. However, as many as 2 protein isoforms have been identified. It is localized to the lysosomes of the cell. In terms of tissue specificity, it is notably expressed in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues. This protein is known to be N-glycosylated and cleaved. Other names for this target antigen include CLN2, CLN2, and GIG1.
The detection range for different tripeptidyl peptidase I ELISA kits can vary, with some assays measuring target concentrations as low as 0.15 ng/mL and as high as 10 ng/mL. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.