The following sphingosine kinase 2 ELISA kits are useful research tools for the measurement of sphingosine kinase 2 in biological samples. In humans this protein is encoded by the SPHK2 gene. This protein is known to catalyze the phosphorylation of sphingosine to form sphingosine-1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. The canonical protein structure is reported to have an amino acid sequence of 654 residues and a mass of 69.2 kDa. Its subcellular location is known to be in the nucleus, mitochondria, ER, and cytoplasm. In addition, it is reported to be mainly expressed in adult kidney, liver, and brain. As many as 5 protein isoforms have been reported. In certain instances, it is also post-translationally cleaved and phosphorylated.
There are sphingosine kinase 2 ELISA kits that can detect a target at concentrations as low as 31.25 pg/mL and as high as 5 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.